Table 58.2. Antineoplastic Drug Preparations and Storage
Name How Diluent Storage Other
Supplied Before
Reconstitution
Asparaginase 10,000 sterile water, refrigerate discard unused
ElsparR unit vial saline portion
MSD
Bleomycin 15 unit sterile water refrigerate
Sulfate vial saline
BlenoxaneR 5% dextrose in
Mead-Johnson water
Carboplatin 50 mg vial sterile water, RT* Stable at 25o C for
ParaplatinR 150 mg saline, 8 h
Bristol vial 5% dextrose in No aluminum hubbed
450 mg water needles
vial
Carmustine 100 mg supplied diluent refrigerate Discard unused
BiCNUR vial (ethanol) portion
Bristol sterile water
Cisplatin 10 mg vial sterile water RT Never give to cats
PlatinolR 50 mg vial Stable for 20 h
Bristol after dilution
No aluminum hubbed
needles
Cyclophospham 25 mg tabs -- tablets -- RT Do not split
ide 50 mg tabs -- injection -- tablets
CytoxanR 100 mg inj sterile water refrigerate
Mead-Johnson 200 mg inj " after opening
500 mg inj "
1 g inj "
2 g inj "
Cytarabine 100 mg sterile water RT
CytosarR vial saline
Upjohn 500 mg 5% dextrose in
vial water
Dacarbazine 100 mg sterile water refrigerate
DTICR vial
Miles 200 mg
vial
Dactinomycin 0.5 mg sterile water RT Discard unused
CosmegenR vial portion
MSD
Doxorubicin 10 mg vial saline RT Do not use with
HCL 50 mg vial or heparin
refrigerate
AdriamycinR
Adria Labs
Fluorouracil 500 mg supplied as RT
5FUR vial liquid
Burroughs-
Wellcome
Vinblastine 10 mg vial supplied as refrigerate
VelbanR liquid
Lilly
Vincristine 1 mg vial supplied as refrigerate
sulfate 5 mg vial liquid
OncovinR
Lilly
* RT = Room temperature Modified from Bonney and Knapp 1994.