A-Aminopeptidase M

Part Number: 7547069
Ala-Rho110 is a preferred substrate of aminopeptidase M. The aminopeptidases are a group of enzymes which hydrolyze peptide bonds at the N-terminus of polypeptides. Aminopeptidase M has been identified as the cell surface marker CD13. Aminopeptidase M may have a role in myeloid cell regulation as a negative regulator through inactivation of bioactive peptides. Inhibition of aminopeptidase M has been found to increase such processes as phagocytosis and immune responses to antigen and tumor cell stimuli.
Alternative enzyme nomenclature: alanine aminopeptidase, aminopeptidase N, EC 3.4.11.2

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu