VK-Cathepsin

Part Number: 7547106

Val-lys-Rho110 has been identified as a substrate of cathepsin D and cathepsin B by a screen of many different dipeptide derivatives. Cathepsin D is a lysosomal aspartic proteinase that is released by macrophages and connective tissue cells under inflammatory conditions. Cathepsin D has been studied in breast tissue. Cathepsin B is a lysosomal cysteine endopeptidase that may play a role in the processing of insulin. Cathepsin B may also contribute to cell migration.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu