Immunoglobulin Binding to Proteins A and G, Jacalin and Mannan Binding Protein
David Chambers http://flosun.salk.edu/~davidc
Affinity of Protein G, Protein A, Protein A/G, Mannan Binding Protein and Jacalin for Various Immunoglobulins as Reported in Literature.
|
Protein A |
Protein G |
Protein A/G |
Jacalin |
Mannan Binding Protein |
| Human IgG |
S |
S |
S |
nb |
nb |
| Human IgG1 |
S |
S |
S |
nb |
nb |
| Human IgG2 |
S |
S |
S |
nb |
nb |
| Human IgG3 |
w |
S |
S |
nb |
nb |
| Human IgG4 |
S |
S |
S |
nb |
nb |
| Human IgM |
w |
nb |
w |
- |
S |
| Human IgA |
w |
nb |
w |
S |
- |
| Human IgA1 |
w |
- |
S |
S |
- |
| Human IgA2 |
w |
- |
S |
w |
- |
| Human IgD |
nb |
nb |
w |
- |
- |
| Mouse IgG |
S |
S |
S |
nb |
nb |
| Mouse IgG1 |
w |
w/s |
w/s |
- |
nb |
| Mouse IgG2a |
S |
S |
S |
- |
nb |
| Mouse IgG2b |
S |
S |
S |
- |
nb |
| Mouse IgG3 |
S |
S |
S |
- |
nb |
| Mouse IgM |
nb |
nb |
nb |
- |
S |
| Horse IgG |
w |
S |
S |
- |
- |
| Horse IgG(c) |
w |
nb |
w |
- |
- |
| Horse IgG(T) |
nb |
nb |
nb |
- |
- |
| Rabbit IgG |
S |
S |
S |
nb |
- |
| Goat IgG |
w |
S |
S |
- |
- |
| Rat IgG |
w |
w/s |
w/s |
- |
- |
| Sheep IgG |
w |
S |
S |
- |
- |
| Cow IgG |
w |
S |
S |
- |
- |
| Guinea Pig IgG |
S |
w |
S |
- |
- |
| Pig IgG |
S |
w |
S |
- |
- |
| Dog IgG |
S |
w |
S |
- |
- |
| Cat IgG |
S |
w |
S |
- |
- |
| Monkey IgG (Rhesus) |
S |
S |
S |
- |
- |
| Chicken IgG |
nb |
nb |
nb |
- |
- |
Legend
w : Weak binding
S : Strong binding
w/s : Indifferent
nb : No binding
- : Information not available
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