Greetings Ross,
A good demonstration of the efflux assay was published by
Klimecki et al.
P-glycoprotein expression and function in circulating blood cells from
normal volunteers. Blood, 83: 2451-2458, 1994.
also see:
Gruol et al,
Reversal of multidrug resistance by RU 486.
Cancer Res. 54: 3088-3091, 1994.
Cheers,
Sam Witherspoon sw11527@glaxo.com
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Flow Cytometry and Cell Sorting Resource
Dept. of Receptor Biochemistry
Glaxo Wellcome R&D.
RTP, NC 27709
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