Re: DNAse and TdT apoptosis assay

Russ Boggs (rboggs@isisph.com)
Tue, 16 Jul 1996 09:40:53 -0700

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>We have a client who wants to generate a postive control for the TdT
>apoptosis assay by treating normal cells with DNAse. I have a few questions
>for anyone who has done this.

Jeff,

Why not use a drug like camptothecin or etoposide?

If you really need to use DNase, you should try to find some of the in vivo
footprinting studies (sorry, I can't remember the citations)

--Russ Boggs

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