RE: Lipid staining

Bob Ashcroft (cytomat@netcore.com.au)
Fri, 14 Nov 1997 09:54:56 +1100

Keith,
Try UV excitation of cis/trans(?) parinaric acid?
Larry Sklar did some work on this lipid, but I don't recall if it was by flow.
Bob
-----Original Message-----
From: Keith Bahjat [SMTP:kbahjat@ufl.edu]
Sent: Thursday, November 13, 1997 1:51 PM
To: Cytometry Mailing List
Subject: Lipid staining

I am attempting to stain neutral lipid bodies within dendritic cells for
the purpose of enumeration (per cell, as well as cells containing
inclusions) and am having trouble finding an adequate procedure.

I have tried Nile Red with and without glutaraldehyde fixation of the
cells, but the background is too high to delineate positive from
negative.

My hope is to find a narrow bandwdth dye that will allow simulataneous
detection of typical fluorochromes, but I'll take what I can get.

Any suggestions appreciated.

Thanks.

--
Keith Bahjat
Graduate Assistant
University of Florida
College of Medicine
Gainesville, Florida
kbahjat@ufl.edu