We briefly mention the fact that some SCID mice can be leaky. Rag 2-/-
mice however are not known to be leaky. We are currently drafting a new
paper which is a direct comparison of SCID (2 different backgrounds) and
Rag 2-/- mice, but it is not ready to send out yet.
Best wishes,
Rochelle Diamond
Caltech Flow Cytometry/Cell Sorting Facility
On Fri, 20 Sep 1996, Meenakshi Roy wrote:
>
> Hi everyone,
> I am planning some cell transfer experiments to look at developmental
> potential of sorted T cell subsets. I am trying to weigh the
> merits/demerits of using SCID mice versus RAG deficient mice for this
> purpose.
> Does anyone have any insights on this? I would greatly appreciate your
> feedback and can undertake to post a summary on the newsgroup.
> Thanks\
> Meenakshi
>
>
>